代表性论文（*第一作者，^#通讯作者）

亚游app官网下载|开户1. ? ?Duan GF, Ye Y, Xu S, Tao W, Zhao S, Jin T, Nicoll RA, Shi YS#, Sheng N# (2018). Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain. Nat Commun. 9(1):4879.

2. ? ?Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, Ye C, Shi YS and Liu JJ.(2018) Postsynaptic Endophilin A1 Regulates Synaptic Plasticity and Long-term Memory. Front Mol Neusci. 11:177.

3. ? ?Sheng N, Bemben MA, Díaz-Alonso J, Tao W, Shi YS, Nicoll RA. (2018) LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes. Proc Natl Acad Sci U S A. 115(15):3948-3953.

4. ? ?Chen J*, Du Y*, He X, Huang X#, Shi YS#. (2017) A Convenient Cas9-based Conditional Knockout Strategy for Simultaneously Targeting Multiple Genes in Mouse. Sci Rep. 7(1):517.

5. ? ?Wei M, Jia M, Zhang J, Yu L, Zhao Y, Chen Y, Ma Y, Zhang W, Shi YS, Zhang C (2017) The Inhibitory Effect of α/β-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors. Front. Mol. Neurosci. 10: Article 55.

6. ? ?Sheng N,?Shi YS, Nicoll RA. (2017) The amino-terminal domains of kainate receptors determine the differential dependence on Neto auxiliary subunits for trafficking.?Proc Natl Acad Sci U S A.?114(5):1159-1164.

7. ? ?Niu Y, Dai Z, Liu W, Zhang C, Yang Y, Guo Z, Li X, Xu C, Huang X, Wang Y,?Shi YS#, Liu JJ#. (2017) Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory.?Elife.?30;6. pii: e20991. [Epub ahead of print].

8. ? ? He XY,?Li YJ,?Kalyanaraman C,?Qiu LL,?Chen C,?Xiao Q,?Liu WX,?Zhang W,?Yang JJ,?Chen G,?Jacobson MP,?Shi YS#. (2016) GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors.?Proc Natl Acad Sci U S A.?113(38):E5645-54.

9. ? ?Qiu LL, Luo D, Zhang H,?Shi YS, Li YJ, Wu D, Chen J, Ji MH, Yang JJ.(2016)?Nox-2-Mediated Phenotype Loss of Hippocampal Parvalbumin Interneurons Might Contribute to Postoperative Cognitive Decline in Aging Mice.?Front Aging Neurosci.?8:234.

10. ?Zhang L, Zhou J, Han J, Hu B, Hou N,?Shi Y, Huang X, Lou X.（2016）Generation of an Oocyte-Specific Cas9 Transgenic Mouse for Genome Editing.?PLoS One.?Apr 27;11(4):e0154364.

11. ?Wei M, Zhang J, Jia M, Yang C, Pan Y, Li S, Luo Y, Zheng J, Ji J, Chen J, Hu X, Xiong J,?Shi Y, Zhang C.(2016)?α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors.?Proc Natl Acad Sci U S A.?May 10; 113(19):E2695-704.

12. ?Hou JX, Cheng SS, Chen L, Wang QH,?Shi Y, Xu Y, Yin ZY, Chen GQ. (2016)?Astroglial Activation and Tau Hyperphosphorylation Precede to Neuron Loss in a Neurodegenerative Mouse Model.?CNS Neurosci Ther.?Mar;22(3):244-7.

13. ?Sheng N,?Shi YS, Lomash RM, Roche KW, Nicoll RA. (2015) Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1.?Elife.?pii: e11682.

14. ?Cheng S, Hou J, Zhang C, Xu C, Wang L, Zou X, Yu H,?Shi Y, Yin Z, and Chen G. (2015) Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurodegeneration.?Scientific reports?5, 10535.

15. ?Granger AJ,?Shi Y, Lu W, Cerpas M, Nicoll RA. (2013) LTP requires an extrasynaptic pool of glutamate receptors independent of subunit type.?Nature.?493(7433)，495-500.

16. ?Herring B*,?Shi Y*, Suh YH, Zheng CY, Schmid SM, Roche KW, Nicoll RA. (2013) Cornichon proteins determine the subunit composition of synaptic AMPA receptors.?Neuron.?77(6),1083-96.

17. ?Gray JA,?Shi Y, Usui H, During MJ, Sakimura K, Nicoll RA. (2011) Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: analysis of single-cell GluN2 subunit deletion in vivo.?Neuron.??71(6),?1085-1101.

18. ?Shi Y*, Suh YH*, Milstein AD, Isozaki K, Schmid SM, Roche KW, Nicoll RA. (2010) Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.?Proc Natl Acad Sci U S A.?107(37), 16315-16319.

19. ?Shi Y,?Lu W, Milstein AD, Nicoll RA. (2009) The stoichiometry of AMPA receptors and TARPs varies by neuronal cell types.?Neuron.?62(5), 633-40.

20. ?Lu W,?Shi Y,?Jackson A, Bjorgan K, During MJ, Sprengel R, Seeburg PH, Nicoll RA. (2009) Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.?Neuron.?62(2), 254-68.

21. ?Shi Y*, Chen X*, Wu Z, Shi W, Jiang C, Harrison R. (2008)?cAMP-dependent protein kinase phosphorylation produces interdomain movements in SUR2B leading to activation of vascular KATP?channel.?Journal of Biological Chemistry.283(12),?7523-30.

22. ?Shi Y,?Cui N, Shi W, Jiang C. (2008) A short motif in Kir6.1 consisting of 4 phosphorylation repeats underlies vascular KATP?channel inhibition by protein kinase C.?Journal of Biological Chemistry.?283(5),?2488-94.

23. ?Shi Y,?Wu Z, Cui N, Shi W, Yang Y, Zhang X, Rojas A, Ha BT, Jiang C. (2007) PKA phosphorylation on SUR2B subunit underscores vascular KATP?channel activation by β-adrenergic receptors.?American Journal of Physiology.?293(3), R1205-14.